html,body{height:100%;overflow:hidden;display:flex;flex-direction:column}#app{flex:1;min-height:0;display:grid;grid-template-columns:260px 1fr 300px 0;overflow:hidden;transition:grid-template-columns .2s ease}body.sp-open #app{grid-template-columns:260px 1fr 300px 320px}#left-panel{background:var(--panel-bg);border-right:1px solid var(--border);display:flex;flex-direction:column;overflow-y:auto;overflow-x:hidden;padding:10px 10px 16px;gap:12px;min-width:0}#center-panel{display:flex;flex-direction:column;overflow:hidden;background:var(--white);min-width:0}#right-panel{background:var(--panel-bg);border-left:1px solid var(--border);display:flex;flex-direction:column;overflow-y:auto;overflow-x:hidden;padding:10px 10px 16px;gap:8px;min-width:0}#toolbar{display:flex;align-items:center;gap:3px;padding:6px 10px;background:var(--white);border-bottom:1px solid var(--border);flex-shrink:0;flex-wrap:wrap;min-height:42px}.view-toggle{display:flex;gap:3px}.view-toggle .tb-btn.active{background:var(--orange);border-color:var(--orange);color:var(--white)}#canvas-wrap{flex:1;position:relative;min-height:0;overflow-y:auto;overflow-x:hidden;background:var(--white)}#gsea-canvas{display:block;width:100%}#canvas-placeholder{position:absolute;inset:0;display:flex;flex-direction:column;align-items:center;justify-content:center;gap:10px;color:var(--gray-dark);font-size:14px;pointer-events:none;text-align:center;padding:20px}#canvas-placeholder .ph-icon{font-size:42px;opacity:.25;line-height:1}#canvas-placeholder p{font-size:13px;color:var(--gray-dark);max-width:320px;line-height:1.5}#stats-strip{display:flex;align-items:center;gap:20px;padding:4px 14px;background:var(--gray-light);border-top:1px solid var(--border);font-size:11px;color:var(--gray-dark);flex-shrink:0}.stat-item{display:flex;align-items:center;gap:4px}.stat-label{opacity:.75}.stat-val{font-weight:600;color:var(--text)}.panel-section{display:flex;flex-direction:column;gap:7px}.section-title{font-size:10px;font-weight:700;letter-spacing:.08em;color:var(--gray-dark);text-transform:uppercase;padding-bottom:4px;border-bottom:1px solid var(--border)}.mode-toggle{display:flex;gap:3px}.mode-toggle .tb-btn{flex:1;text-align:center}#rank-textarea{width:100%;min-height:130px;max-height:260px;font-family:Menlo,Consolas,monospace;font-size:11px;padding:7px 8px;border:1px solid var(--border);border-radius:var(--radius);resize:vertical;background:var(--white);color:var(--text);line-height:1.45}#rank-textarea:focus{outline:none;border-color:var(--orange)}#drop-zone{border:2px dashed var(--border);border-radius:var(--radius);padding:16px 10px;text-align:center;cursor:pointer;transition:all .15s;background:var(--white);font-size:12px;color:var(--gray-dark);line-height:1.5}#drop-zone:hover,#drop-zone.drag-over{border-color:var(--orange);background:var(--orange-bg);color:var(--orange)}#data-summary{background:#edf7ed;border:1px solid #b2dfb2;border-radius:var(--radius);padding:5px 9px;font-size:11px;color:#2e6b2e}.gmt-drop{display:flex;align-items:center;justify-content:space-between;gap:6px;border:1px dashed var(--border);border-radius:var(--radius);padding:7px 9px;font-size:11px;color:var(--gray-dark);cursor:pointer;background:var(--white)}.gmt-drop:hover{border-color:var(--orange)}#results-summary{font-size:11px;color:var(--gray-dark);padding:2px 0}.ctrl-row{display:flex;align-items:center;gap:6px;font-size:12px}.ctrl-row label{flex-shrink:0;width:82px;color:var(--gray-dark);font-size:11px}.ctrl-row select,.ctrl-row input[type=number],.ctrl-row input[type=text]{flex:1;min-width:0;font-size:12px;padding:3px 6px;border:1px solid var(--border);border-radius:var(--radius);background:var(--white);color:var(--text)}.ctrl-row select:focus,.ctrl-row input:focus{outline:none;border-color:var(--orange)}.rp-title{font-size:10px;font-weight:700;letter-spacing:.08em;color:var(--gray-dark);text-transform:uppercase;padding-bottom:4px;border-bottom:1px solid var(--border);display:flex;align-items:center;gap:5px}.rp-count{font-size:11px;color:var(--orange);font-weight:600;letter-spacing:0;text-transform:none}.rp-actions{display:flex;gap:4px}#set-list{display:flex;flex-direction:column;gap:1px;max-height:38vh;overflow-y:auto}.set-row{display:flex;align-items:center;justify-content:space-between;gap:8px;padding:4px 7px;border-radius:4px;cursor:pointer;font-size:12px;border:1px solid transparent;transition:background .1s}.set-row:hover{background:var(--gray-light)}.set-row.selected{background:#fff8f0;border-color:var(--orange)}.set-row-name{flex:1;min-width:0;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;color:var(--text)}.set-row-nes{flex-shrink:0;font-variant-numeric:tabular-nums;font-weight:600;font-size:11px}#le-list{flex:1;overflow-y:auto;min-height:40px;display:flex;flex-direction:column;gap:2px}.gene-chip{font-size:11px;padding:3px 8px;border-radius:4px;background:var(--down-lt);color:#1a5a8a;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:Menlo,Consolas,monospace}.rp-empty{font-size:12px;color:var(--gray-dark);padding:4px 2px}.rp-hint{margin-top:auto;padding-top:12px;font-size:11px;color:var(--gray-dark);line-height:1.55;border-top:1px solid var(--border)}.db-loading{display:flex;align-items:center;justify-content:center;gap:8px;padding:20px;color:var(--gray-dark);font-size:13px}.spinner{width:18px;height:18px;border:2px solid var(--border);border-top-color:var(--orange);border-radius:50%;animation:spin .6s linear infinite}@keyframes spin{to{transform:rotate(360deg)}}#btn-customize.active{background:var(--orange);border-color:var(--orange);color:var(--white)}#btn-customize.active .action-icon{filter:brightness(0) invert(1)}.style-panel{background:var(--panel-bg);border-left:1px solid var(--border);display:flex;flex-direction:column;overflow:hidden;min-width:0;width:100%;grid-column:4}.style-panel.hidden{display:flex}.sp-header{display:flex;align-items:center;justify-content:space-between;padding:10px 14px;background:var(--white);border-bottom:1px solid var(--border);flex-shrink:0}.sp-title{font-size:13px;font-weight:700;color:var(--navy)}.sp-close{width:26px;height:26px;border:none;background:transparent;font-size:22px;line-height:1;color:var(--gray-dark);cursor:pointer;border-radius:var(--radius);transition:background .12s}.sp-close:hover{background:var(--gray-light);color:var(--text)}.sp-tabs{display:flex;flex-wrap:wrap;gap:2px;padding:6px 8px;background:var(--white);border-bottom:1px solid var(--border);flex-shrink:0}.sp-tab{padding:4px 8px;font-size:11px;font-weight:500;border:1px solid var(--border);border-radius:var(--radius);background:var(--white);color:var(--gray-dark);cursor:pointer;transition:all .12s}.sp-tab:hover{border-color:var(--orange);color:var(--orange)}.sp-tab.active{background:var(--orange);border-color:var(--orange);color:var(--white)}.sp-body{flex:1;overflow-y:auto;overflow-x:hidden;padding:8px 12px 12px}.sp-footer{padding:8px 12px;background:var(--white);border-top:1px solid var(--border);display:flex;justify-content:flex-end;gap:6px;flex-shrink:0}.sp-group{margin-top:6px;padding:10px 0 6px;border-bottom:1px solid var(--border)}.sp-group:last-child{border-bottom:none}.sp-group-title{font-size:10px;font-weight:700;letter-spacing:.6px;text-transform:uppercase;color:var(--gray-dark);margin-bottom:8px}.sp-row{display:flex;align-items:center;gap:8px;margin-bottom:7px;min-height:26px}.sp-label{font-size:11px;color:var(--text);width:92px;flex-shrink:0}.sp-controls{display:flex;align-items:center;gap:4px;flex:1;min-width:0;flex-wrap:wrap}.sp-num{width:64px;padding:3px 6px;font-size:12px;border:1px solid var(--border);border-radius:var(--radius);background:var(--white);color:var(--text)}.sp-num:focus{outline:none;border-color:var(--orange)}.sp-text{flex:1;min-width:0;padding:4px 7px;font-size:12px;border:1px solid var(--border);border-radius:var(--radius);background:var(--white);color:var(--text)}.sp-text:focus{outline:none;border-color:var(--orange)}.sp-select{flex:1;min-width:0;padding:3px 4px;font-size:12px;border:1px solid var(--border);border-radius:var(--radius);background:var(--white);color:var(--text)}.sp-select:focus{outline:none;border-color:var(--orange)}.sp-color{width:32px;height:26px;padding:0;border:1px solid var(--border);border-radius:var(--radius);cursor:pointer;background:var(--white);flex-shrink:0}.sp-check{display:flex;align-items:center;gap:6px;font-size:12px;color:var(--text);cursor:pointer;user-select:none}.sp-check input{width:14px;height:14px;cursor:pointer;accent-color:var(--orange)}.sp-hint{font-size:10px;color:var(--gray-dark);margin-top:6px;line-height:1.45;font-style:italic}.sp-empty{font-size:12px;color:var(--gray-dark);padding:8px 0}.sp-preset-item{display:flex;align-items:center;justify-content:space-between;padding:6px 0;border-bottom:1px solid var(--border)}.sp-preset-item:last-child{border-bottom:none}.sp-preset-name{font-size:12px;font-weight:600;color:var(--text);flex:1;overflow:hidden;text-overflow:ellipsis;white-space:nowrap}.sp-preset-actions{display:flex;gap:4px}@media (max-width:1100px){#app{grid-template-columns:260px 1fr 300px 0}body.sp-open #app{grid-template-columns:260px 1fr 0 320px}body.sp-open #right-panel{display:none}}@media (max-width:960px){#right-panel{display:none}#app{grid-template-columns:260px 1fr 0 0}body.sp-open #app{grid-template-columns:260px 1fr 0 300px}}@media (max-width:620px){#left-panel,.style-panel{display:none}#app{grid-template-columns:1fr}}